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Eczema, a chronic skin condition marked by inflammation and irritation, often leaves individuals grappling with a persistent question: Why does eczema itch? The answer lies in the compromised barrier function of the skin. Eczema disrupts the skin's natural protective layer, facilitating the penetration of irritants that trigger an immune response. This immune reaction releases inflammatory chemicals, like histamines, intensifying the itching sensation.

Additionally, individuals with eczema experience heightened nerve sensitivity, amplifying the perception of itchiness. Strikingly, the act of scratching, a natural response to alleviate discomfort, paradoxically worsens the condition by causing further damage to the skin barrier.

The intricate connection between immune responses, nerve sensitivity, and compromised skin barrier sheds light on the mystery of eczema-related itching. Understanding these underlying mechanisms is crucial for developing targeted therapies aimed at breaking the cycle of inflammation and itching, offering hope for improved relief and management of eczema symptoms. https://chinesedoc.sg/itch-inflammation-moisture-barrier-dysfunction/